Frequently Asked Questions

The following questions and answers should help clear up any confusion you might have about frequent heartburn.

Heartburn is a painful burning sensation in the lower chest caused by acid reflux. Acid from the stomach moves back (or “refluxes”) into the esophagus, often causing heartburn pain.
Heartburn that occurs two or more days a week.
Acidic fruits such as oranges, lemons, grapefruits and tomatoes; high-fat or spicy foods; chocolate, alcohol and coffee.
There are multiple factors including but not limited to smoking, being overweight, taking certain medications, eating before bedtime and wearing tight-fitting clothing.
Zegerid OTC® is the only 24-hour frequent heartburn treatment that contains two active ingredients: the leading prescription acid reducer (omeprazole), plus a second ingredient (sodium bicarbonate) that protects the omeprazole from acid in the stomach — so it can be absorbed by the body and get right to work treating frequent heartburn.
Zegerid OTC® is for use by adults 18 and older for the treatment of frequent heartburn (occurs two or more days a week). For more information, see our full product label.
One Zegerid OTC® capsule (daily dose) contains 303 mg of sodium. This amount is comparable to the amount of sodium in two slices of white bread (300 mg). Ask a doctor before use if you have a sodium-restricted diet.
Proton Pump Inhibitors (PPIs), such as Zegerid OTC®, are medicines specifically indicated for treating frequent heartburn. They are highly effective because they block acid production at the source by deactivating acid pumps in your stomach. And PPIs only need to be taken once a day for 14 days.
From an active ingredient perspective, there is no difference between Zegerid OTC® 20 mg capsule and prescription Zegerid® 20 mg capsule. While they contain the same active ingredients, the dosage strengths and indications differ between prescription Zegerid® and Zegerid OTC®. Zegerid OTC® is available in a 20 mg strength and is indicated for frequent heartburn. Prescription Zegerid® is available as both 20 mg and 40 mg strengths, and is indicated for conditions that require a doctor’s diagnosis and treatment.
Yes. Physicians will still be able to prescribe Zegerid® as appropriate.
For more information on prescription Zegerid®, visit
Zegerid OTC® capsules are available over the counter in stores nationwide, including drug stores, grocery stores and mass retailers.